In this pooled analysis of more than 7700 ovarian cancer patients and nearly 12,000 controls, low dose aspirin and high dose non-aspirin NSAID use was associated with a risk reduction for invasive epithelial ovarian cancer of 20 to 34% relative to non-users.
In a nested, case-control analysis using a large computerized clinical dataset, a 16% reduction in colorectal cancer incidence was observed after 3 or more years of angiotensin inhibitor and/or angiotensin receptor blocker treatment of hypertension.
After a median follow-up of 5 years, the aromatase inhibitor, anastrozole decreased the incidence of breast cancer in high-risk postmenopausal women by 53% compared to women receiving a placebo.
Synopsis: In this study, the authors evaluated and refined previously published risk stratification for locoregional failure (LF) by applying it to a multicenter patient cohort.
